HIRSCHHORN LAB
Boston Children's Hospital · Broad Institute of MIT and Harvard · Harvard Medical School
PEOPLE
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Joel Hirschhorn
M.D., Ph.D.
Principal Investigator
Joel is the chief of the Division of Endocrinology at Boston Children's Hospital and is the Concordia Professor of Pediatrics and Professor of Genetics at Harvard Medical School.

Angeliki Angelidi
M.D., Ph.D.
Postdoctoral Fellow
Angeliki joined the lab as a postdoctoral fellow in 2021 and has a great interest in Diabetes, Obesity, and Metabolism. She is currently working on genomic and metabolomic data to combine genetics and metabolomics for the identification of metabolites as potential correlates, predictors, or ideally causal mediators of obesity, diabetes, and glycemic traits.

Christina M. Astley
M.D., Sc.D.
Assistant Professor
Christina is an Assistant Professor of Pediatrics at Harvard Medical School and physician-scientist in the Divisions of Endocrinology and Computational Epidemiology at Boston Children's Hospital. Her research focuses on the development of innovative methods to understand individual- and population-level disease dynamics (e.g multiple omics, global digital health data streams).

John Baronas
Lab Manager & Research Assistant
John joined the lab in 2019 as a research assistant and works primarily with Dr. Renthal to investigate the genetics of chondrocyte biology and pediatric skeletal growth.

Eric Bartell
Graduate Student
Eric Bartell is a third year graduate student in the Harvard Bioinformatics and Integrative Genomics PhD program. He is interested in interrogating the genetics of height using derived phenotypes, and the interplay of selection on these phenotypes' genetic architectures.

As a co-mentored postdoc in the labs of Joel Hirschhorn and Jose Florez, Joanne's work is focused on identifying genetic determinants and elucidating genetic architecture of dietary habits by taking multiple complementary approaches to phenotype derivation. Her interests lie in novel data-driven approaches to making sense out of large complex datasets of correlated normal human variation and linking these traits, such as diet, to human health and disease. She also applies similar methods and ideas to disease phenotypes, working currently with the devastating diabetes complication, diabetic kidney disease.

Yisong Huang
Biostatistician

Jonah Kaziyev
Research Assistant

Varada Krishnadas
Research Assistant

Nora Renthal
M.D., Ph.D.
Instructor
Nora is a pediatric endocrinologist and basic science investigator interested in the genetics of pediatric skeletal growth. She joined the Hirschhorn Lab as an instructor in 2019 after endocrine fellowship at Boston Children's Hospital. She received her MD and PhD from the University of Texas Southwestern Medical Center.

Sailaja Vedantam
Ph. D.
Research Scientist
Sailaja is working on large-scale computational analysis of genome-wide association studies and is interested in understanding the role of both common and rare variants in complex traits.
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Hannah Whitley
Administrator
Hannah is a Program Coordinator who joined the lab in 2016. She supports the Hirschhorn Lab as well as the Division of Endocrinology at Boston Children’s Hospital.

Jia Zhu
M.D.
Instructor
Jia is a pediatric endocrinologist and computational genetics investigator. Her research interests are in understanding the biological pathways and mechanisms underlying the pathophysiology of common reproductive endocrine disorders through computational genetic methods, with a focus on pediatric antecedents to adult disorders.
AFFILIATES

Frances Lopez
Ph.D.
Assistant Professor