HIRSCHHORN LAB
Boston Children's Hospital · Broad Institute of MIT and Harvard · Harvard Medical School
PEOPLE
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Joel Hirschhorn
M.D., Ph.D.
Principal Investigator
Joel is the chief of the Division of Endocrinology at Boston Children's Hospital and is the Concordia Professor of Pediatrics and Professor of Genetics at Harvard Medical School.
Angeliki Angelidi
M.D., Ph.D.
Postdoctoral Fellow
Angeliki joined the lab as a postdoctoral fellow in 2021 and has a great interest in Diabetes, Obesity, and Metabolism. She is currently working on genomic and metabolomic data to combine genetics and metabolomics for the identification of metabolites as potential correlates, predictors, or ideally causal mediators of obesity, diabetes, and glycemic traits.
Christina M. Astley
M.D., Sc.D.
Assistant Professor
Christina is an Assistant Professor of Pediatrics at Harvard Medical School and physician-scientist in the Divisions of Endocrinology and Computational Epidemiology at Boston Children's Hospital. Her research focuses on the development of innovative methods to understand individual- and population-level disease dynamics (e.g multiple omics, global digital health data streams).
John Baronas
Lab Manager & Research Assistant
John joined the lab in 2019 as a research assistant and works primarily with Dr. Renthal to investigate the genetics of chondrocyte biology and pediatric skeletal growth.
Mali DiMeo
Research Assistant
Anders Eliasen
M.Sc., Ph.D.
Postdoctoral Fellow
Anders joined the lab in 2022 as a postdoctoral fellow. He is interested in computational methods for genome-wide association studies and is currently working with genetic data to examine how a genetic predisposition for obesity influence childhood traits predating the onset of obesity.
Wen He
Postdoctoral Fellow
Wen joined the lab as a postdoc research fellow in 2023. Wen's research interest is in understanding the neuroendocrine regulation of reproductive function and related reproductive endocrine disorders through computational genetic methods. Wen is currently focusing on identifying both common and rare genetic associations with diseased populations using large biobank genetic data.
Yisong Huang
Biostatistician
Varun Lingadal
Research Assistant
Varun joined the lab in the summer of 2023 as a Research Assistant. He is currently working with Dr. Zhu to investigate the genetics of PCOS and with Dr. Lopez to study the effects of certain pharmacological agents on neuronal activity. Varun graduated from Dartmouth College with a Bachelor of Arts in Biology modified with Mathematics.
Nora Renthal
M.D., Ph.D.
Instructor
Nora is a pediatric endocrinologist and basic science investigator interested in the genetics of pediatric skeletal growth. She joined the Hirschhorn Lab as an instructor in 2019 after endocrine fellowship at Boston Children's Hospital. She received her MD and PhD from the University of Texas Southwestern Medical Center.
Aishwarya Seth
Research Assistant
Aishwarya has a Master’s in Biomedical Engineering from Johns Hopkins, with a background in computer science, and joined the Hirschhorn Lab in 2023. She has built machine learning based predictive models to predict the risk of diseases using imaging and clinical data. She works towards identifying genetic predisposing factors that impact disease risk and anthropometric traits.
Jia Zhu
M.D.
Instructor
Jia is a pediatric endocrinologist and computational genetics investigator. Her research interests are in understanding the biological pathways and mechanisms underlying the pathophysiology of common reproductive endocrine disorders through computational genetic methods, with a focus on pediatric antecedents to adult disorders.
AFFILIATES
Frances Lopez
Ph.D.
Assistant Professor